1) Haemopoietic stem cell transplantation A) Haematological malignancies B) Severe Haemoglobinopathies C) Aplastic anemia D) Primary immune deficiencies 2) Stem cells delivery for tissue regeneration A) Neurological diseases B) Diabetes C) Cardiac failure D) Cartilage and bone disorders E) Skin and skin-appendage disorders F) Others 3) Stem cells as vectors for gene therapy Delivery of a therapeutic gene to the desired cell type by genetically transduced hemopoietic stem cells